2-Iodobenzoic acid → 4-Amino-3-(o-carboxyphenylthio)benzoic Acid

HRID 444155

反応式

HRID 444155 の反応式
[SH:1][C:2]1[CH:3]=[C:4]([CH:8]=[CH:9][C:10]=1[NH2:11])[C:5]([OH:7])=[O:6].I[C:13]1[CH:21]=[CH:20][CH:19]=[CH:18][C:14]=1[C:15]([OH:17])=[O:16]>[Cu]>[NH2:11][C:10]1[CH:9]=[CH:8][C:4]([C:5]([OH:7])=[O:6])=[CH:3][C:2]=1[S:1][C:13]1[CH:21]=[CH:20][CH:19]=[CH:18][C:14]=1[C:15]([OH:17])=[O:16]

参加物

4

反応物 2

HCID 69412-Iodobenzoic acidHCID 5980584-Amino-3-mercaptobenzoic acid

生成物 1

HCID 234644884-Amino-3-(o-carboxyphenylthio)benzoic Acid

試薬・触媒・溶媒 1

HCID 23978Copper触媒

実験手順

Reflux a mixture of 200 ml of the 50% potassium hydroxide solution of Step A, 24.15 gm (97 mmoles) of o-iodobenzoic acid and 7.5 gm of copper metal powder for 11/2 hours. Cool the mixture and filter. Dilute the filtrate to twice its volume with water and acidify. Separate the solids by filtration, wash well with water and air dry.

後処理

  1. temperatureReflux
  2. temperatureCool the mixture
  3. filtrationfilter
  4. additionDilute the filtrate to twice its volume with water
  5. customSeparate the solids
  6. filtrationby filtration
  7. washwash well with water and air
  8. customdry

出典と根拠

ORDレコード
ord-729869e585f3488ea62039d0517b3713
出典データセット
uspto-grants-1981_04
特許番号
US04263207

関連ノート

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