4-Hydroxybenzaldehyde → Benzaldehyde, 4-(acetyloxy)-

HRID 446197

反応式

HRID 446197 の反応式
[OH:1][C:2]1[CH:9]=[CH:8][C:5]([CH:6]=[O:7])=[CH:4][CH:3]=1.[C:10](OC(=O)C)(=[O:12])[CH3:11]>N1C=CC=CC=1>[C:10]([O:1][C:2]1[CH:9]=[CH:8][C:5]([CH:6]=[O:7])=[CH:4][CH:3]=1)(=[O:12])[CH3:11]

参加物

4

反応物 2

HCID 1264-HydroxybenzaldehydeHCID 7918Acetic Anhydride

生成物 1

HCID 70144Benzaldehyde, 4-(acetyloxy)-収率 93%

試薬・触媒・溶媒 1

HCID 1049Pyridine溶媒

実験手順

To the solution of 4-hydroxybenzaldehyde (10.0 g, 81.9 mmol) in 150 ml of pyridine was added acetic anhydride (60 ml). The resultant mixture was stirred at room temperature for 2 hours. After removal of the solvent, the compound was purified by flash chromatography using heptane/methylene chloride/ethyl acetate (20/20/10) as eluent in a yield of 93%.

後処理

  1. customAfter removal of the solvent
  2. customthe compound was purified by flash chromatography

出典と根拠

ORDレコード
ord-a3854bd679c14cadbdebfa4ffdf351e0
出典データセット
uspto-grants-2013_07
特許番号
US08476450B2

関連ノート

読み込み中…