Thionyl Chloride → 2,6-Dichloro-4-iodobenzoyl chloride

HRID 449917

反応式

HRID 449917 の反応式
[Cl:1][C:2]1[CH:10]=[C:9]([I:11])[CH:8]=[C:7]([Cl:12])[C:3]=1[C:4](O)=[O:5].O=S(Cl)[Cl:15]>>[Cl:1][C:2]1[CH:10]=[C:9]([I:11])[CH:8]=[C:7]([Cl:12])[C:3]=1[C:4]([Cl:15])=[O:5]

参加物

3

反応物 2

HCID 24386Thionyl ChlorideHCID 513418772,6-Dichloro-4-iodobenzoic acid

生成物 1

HCID 866489582,6-Dichloro-4-iodobenzoyl chloride収率 100%

実験手順

A solution of 2,6-dichloro-4-iodobenzoic acid (65 mg, 0.21 mmol) in SOCl2 (3 mL) was heated to reflux under nitrogen atmosphere overnight and then cooled to room temperature. The reaction was conentrated under reduced pressure to afford 2,6-dichloro-4-iodobenzoyl chloride (70 mg, 100% yield).

後処理

  1. temperatureto reflux under nitrogen atmosphere overnight

出典と根拠

ORDレコード
ord-4d56422000ae457ca41ed97b75cb9c61
出典データセット
uspto-grants-2013_07
特許番号
US08486950B2

関連ノート

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