5-Nitro-1H-indole-2-carboxylic acid propylamide → 5-Amino-1H-indole-2-carboxylic acid propylamide
反応式
[CH2:1]([NH:4][C:5]([C:7]1[NH:8][C:9]2[C:14]([CH:15]=1)=[CH:13][C:12]([N+:16]([O-])=O)=[CH:11][CH:10]=2)=[O:6])[CH2:2][CH3:3]>CCO.[Pd]>[CH2:1]([NH:4][C:5]([C:7]1[NH:8][C:9]2[C:14]([CH:15]=1)=[CH:13][C:12]([NH2:16])=[CH:11][CH:10]=2)=[O:6])[CH2:2][CH3:3]参加物
4
実験手順
To a solution of 5-nitro-1H-indole-2-carboxylic acid propylamide (2.94 g, 11.9 mmol) in EtOH (150 ml) a suspension of palladium on charcoal (10%, 1 g) in EtOH was added. The mixture was hydrogenated at atmospheric pressure. After filtration and removal of the solvents in vacuo the product was obtained as a yellow powder (2.46 mg, 95%).
後処理
- additionwas added
- filtrationAfter filtration and removal of the solvents in vacuo the product
出典と根拠
- ORDレコード
- ord-630127751cc1404dbcd018eddda7be57
- 出典データセット
- uspto-grants-2013_07
- 特許番号
- US08486984B2
反応ノート
読み込み中…