Water → HCID 23712813、化合物
反応式
[CH:1]([N:4]1[CH2:9][CH2:8][CH:7]([C:10]([O:12]CC)=[O:11])[CH2:6][CH2:5]1)([CH3:3])[CH3:2].O.[OH-].[Li+:17]>O1CCCC1>[CH:1]([N:4]1[CH2:5][CH2:6][CH:7]([C:10]([O-:12])=[O:11])[CH2:8][CH2:9]1)([CH3:3])[CH3:2].[Li+:17]参加物
5
実験手順
Ethyl 1-isopropylpiperidine-4-carboxylate (Farmaco., 1993, Vol. 48, p. 1439) (3.43 g) was dissolved in tetrahydrofuran (60 ml), and water (15 ml) and lithium hydroxide (421 mg) were added at room temperature to stir the mixture overnight. The reaction mixture was concentrated under reduced pressure to obtain the title compound (3.05 g) as a white solid.
後処理
- concentrationThe reaction mixture was concentrated under reduced pressure
出典と根拠
- ORDレコード
- ord-d343047cab2a490991646e4f47ef370c
- 出典データセット
- uspto-grants-2007_03
- 特許番号
- US07192968B2
反応ノート
読み込み中…