反応式
[CH3:1][C:2]([C:4]1[CH:12]=[CH:11][C:9]([OH:10])=[C:6](OC)[CH:5]=1)=[O:3].S(OC)([O:16][CH3:17])(=O)=O.[C:20](=O)([O-])[O-].[Na+].[Na+].O>C1C=CC=CC=1>[CH3:1][C:2]([C:4]1[CH:5]=[CH:6][C:9]([O:10][CH3:20])=[CH:11][C:12]=1[O:16][CH3:17])=[O:3]参加物
6
実験手順
10 g of acetovanillone (0.06 mol) was methylated with 10.25 g of dimethyl sulfate (0.083 mol) and 8.0 g of sodium carbonate. The reaction mixture was stirred at 80°-90° C for 2 hr. while 6 ml of water were added dropwise over the last 1.2 hr. Addition of water, acidification, and extraction with benzene produced a nearly quantitative yield of 2,4-dimethoxyacetophenone containing less than 0.3% acetovanillone.
出典と根拠
- ORDレコード
- ord-53ad9b6fae294a6cbcb7f7bd0053547c
- 出典データセット
- uspto-grants-1977_12
- 特許番号
- US04065504
関連ノート
読み込み中…