Ethanolamine → 5-(p-Methoxybenzylidene)-hydantoin

HRID 462209

反応式

HRID 462209 の反応式
[CH3:1][O:2][C:3]1[CH:10]=[CH:9][C:6]([CH:7]=O)=[CH:5][CH:4]=1.[NH:11]1[CH2:17][C:15](=[O:16])[NH:14][C:12]1=[O:13].C(CN)O>O>[CH3:1][O:2][C:3]1[CH:10]=[CH:9][C:6]([CH:7]=[C:17]2[NH:11][C:12](=[O:13])[NH:14][C:15]2=[O:16])=[CH:5][CH:4]=1

参加物

5

反応物 3

HCID 700EthanolamineHCID 10006HydantoinHCID 312444-Methoxybenzaldehyde

生成物 1

HCID 947495-(p-Methoxybenzylidene)-hydantoin収率 85.5%

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

A mixture of p-methoxybenzaldehyde (2.00 g., 14.7 mmoles) and hydantoin (1.47 g., 1 molar ratio) in water (12 ml) was heated to 70°; monoethanolamine (1.35 g., 1.5 molar ratio) was then added. The mixture was stirred magnetically and heated in an oil bath at 90°-92° for 4 hours. Usual workup furnished the title compound as a pale yellow solid (2.74 g.), m.p. 250°-252°.

後処理

  1. temperaturewas heated to 70°
  2. temperatureheated in an oil bath at 90°-92° for 4 hours

出典と根拠

ORDレコード
ord-0f23c96e17954c438e4c4a4db32b7d01
出典データセット
uspto-grants-1977_12
特許番号
US04065571

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