ホーム MCP ワークベンチ Skills

ホームワークベンチ通知マイページ

llms.txt · MCPガイドプライバシーポリシー · 利用規約 · サポートv1.8.0

ホーム
反応

Hydrochloric Acid → 2-(Dimethoxymethyl)-4,6-dihydroxy-2,5,7,8-tetramethylchroman

HRID 462583

印刷プレビュー

反応式

HRID 462583 の反応式

[CH3:1][O:2][CH:3]([O:20][CH3:21])[C:4]1([CH3:19])[CH2:13][C:12](=[O:14])[C:11]2[C:6](=[C:7]([CH3:18])[C:8]([CH3:17])=[C:9]([OH:16])[C:10]=2[CH3:15])[O:5]1.[BH4-].[Na+].[OH-].[Na+].Cl>CO>[CH3:21][O:20][CH:3]([O:2][CH3:1])[C:4]1([CH3:19])[CH2:13][CH:12]([OH:14])[C:11]2[C:6](=[C:7]([CH3:18])[C:8]([CH3:17])=[C:9]([OH:16])[C:10]=2[CH3:15])[O:5]1

参加物実験手順後処理出典と根拠反応ノート

参加物

6

反応物 4

HCID 313Hydrochloric Acid

HCID 14798Sodium Hydroxide

HCID 4311764Sodium borohydride2 回

HCID 130515362-(Dimethoxymethyl)-6-hydroxy-2,5,7,8-tetramethyl-chroman-4-one

生成物 1

HCID 130515402-(Dimethoxymethyl)-4,6-dihydroxy-2,5,7,8-tetramethylchroman収率 95%

試薬・触媒・溶媒 1

HCID 887

Methanol

溶媒

実験手順

9.4 g (32 mmoles) of the product from Example 2 were reacted with 2.43 g (64 mmoles) NaBH4 in 100 ml of methanol at 20°-60° C. After 6 hours, a further 2.43 g of NaBH4 were added, after which the reaction mixture was stirred at room temperature for 16 hours. 100 ml of 3N NaOH were then added, and the mixture was neutralized with dilute hydrochloric acid and then extracted with ether, a brown oil being obtained as the crude product in 95% yield. IR: 3,600 (broad) cm-1.

後処理

extractionextracted with ether

出典と根拠

ORDレコード: ord-3b31a94508974d0fa5a521efc2916cd5
出典データセット: uspto-grants-1985_05
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04515975

反応ノート

読み込み中…

このページの内容参加物実験手順後処理出典と根拠反応ノート