Hydrogen Cyanide → HCID 20283984、化合物

HRID 462661

反応式

HRID 462661 の反応式
ClC1C=[C:4](C(F)(F)F)[CH:5]=[CH:6][C:7]=1[NH2:8].[F:13][C:14]1[CH:15]=[C:16]([C:21]([F:24])([F:23])[F:22])[CH:17]=[CH:18][C:19]=1[NH2:20].C#N.[CH:27](=O)C(C)C>O>[F:13][C:14]1[CH:15]=[C:16]([C:21]([F:22])([F:23])[F:24])[CH:17]=[CH:18][C:19]=1[NH:20][CH:6]([CH:5]([CH3:27])[CH3:4])[C:7]#[N:8]

参加物

6

反応物 4

HCID 768Hydrogen CyanideHCID 6561IsobutyraldehydeHCID 1620012-Chloro-4-trifluoromethylanilineHCID 27376742-Fluoro-4-(trifluoromethyl)aniline

生成物 1

HCID 20283984HCID 20283984、化合物

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

Following the procedure of Example 1, each of 3-chloro-4-aminobenzotrifluoride and 3-fluoro-4-aminobenzotrifluoride is reacted with hydrogen cyanide and isobutyraldehyde, in a neat, initially water-free system, to give the respective nitrile, 2-(2-chloro-4-trifluoro-methylphenylamino)-3-methylbutyronitrile and 2-(2-fluoro-4-trifluoromethylphenylamino)-3-methylbutyronitrile.

出典と根拠

ORDレコード
ord-f4fb8e7036e843d7865338e8ca199b44
出典データセット
uspto-grants-1985_05
特許番号
US04517130

関連ノート

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