Potassium Hydroxide → 1-Chloro-4-(3-phenylpropyl)benzene
反応式
[C:1]1([CH2:7][CH2:8][C:9]([C:11]2[CH:16]=[CH:15][C:14]([Cl:17])=[CH:13][CH:12]=2)=O)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.O.NN.[OH-].[K+]>C(O)COCCO>[Cl:17][C:14]1[CH:13]=[CH:12][C:11]([CH2:9][CH2:8][CH2:7][C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)=[CH:16][CH:15]=1参加物
5
実験手順
p-chlorophenyl phenylethyl ketone (25 g) was refluxed with hydrazine hydrate (13 g) and potassium hydroxide (18 g) in Digol (diethylene glycol) for one hour. The mixture was then distilled until the solution temperature in the still reached 175°. The mixture was then refluxed for 3 hours, cooled, poured into water and extracted with petroleum ether (Bpt 40°-60°). Evaporation of the extracts gave 1-(4-chlorophenyl)-3-phenylpropane Bbt. 110°/10-3 mm.
後処理
- distillationThe mixture was then distilled until the solution temperature in the still reached 175°
- temperatureThe mixture was then refluxed for 3 hours
- temperaturecooled
- additionpoured into water
- extractionextracted with petroleum ether (Bpt 40°-60°)
- customEvaporation of the extracts
出典と根拠
- ORDレコード
- ord-3ea19a854acc474080cbdd3124680918
- 出典データセット
- uspto-grants-1985_05
- 特許番号
- US04520007
反応ノート
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