Sodium Hydroxide → Sulfometuron

HRID 463986

反応式

HRID 463986 の反応式
[CH3:1][C:2]1[CH:7]=[C:6]([CH3:8])[N:5]=[C:4]([NH:9][C:10]([NH:12][S:13]([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=2[C:22]([O:24]C)=[O:23])(=[O:15])=[O:14])=[O:11])[N:3]=1.[OH-].[Na+]>O>[CH3:1][C:2]1[CH:7]=[C:6]([CH3:8])[N:5]=[C:4]([NH:9][C:10]([NH:12][S:13]([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][C:17]=2[C:22]([OH:24])=[O:23])(=[O:15])=[O:14])=[O:11])[N:3]=1

参加物

4

反応物 2

HCID 14798Sodium HydroxideHCID 52997Sulfometuron-methyl

生成物 1

HCID 52998Sulfometuron

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

A mixture of 2.0 g of N-[(4,6-dimethylpyrimidin-2-yl)aminocarbonyl]-2-methoxycarbonylbenzenesulfonamide and 11 ml. of 50% aqueous sodium hydroxide was warmed on a steam bath with shaking; 40 ml. of water was added and heating and shaking continued during the next half hour. The resulting solution was then filtered and the filtrate acidified with hydrochloric acid to pH 2 to yield a precipitate which was isolated by filtration to yield the title compound, 0.7 g melting at 160° with decomposition. The nuclear magnetic resonance spectrum showed resonance peaks for the methyl substituents on the pyrimidine ring at 2.66 ppm and the ring hydrogens at 7.2 to 8.4 ppm. The disappearance of the resonance peak at 4.0 ppm confirmed the conversion of the methyl ester to the carboxy group.

後処理

  1. temperatureheating
  2. stirringshaking
  3. customcontinued during the next half hour
  4. filtrationThe resulting solution was then filtered
  5. customto yield a precipitate which
  6. customwas isolated by filtration

出典と根拠

ORDレコード
ord-8ce8683ec06e4fed8a48f841fbab6b00
出典データセット
uspto-grants-1985_10
特許番号
US04545808

関連ノート

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