Methanol → 3-Phenyl-1-indanone oxime

HRID 464689

反応式

HRID 464689 の反応式
[C:1]1([CH:7]2[C:15]3[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=3)[C:9](=O)[CH2:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.CO.C(=O)([O-])[O-].[K+].[K+].Cl.[NH2:26][OH:27]>O>[OH:27][N:26]=[C:9]1[C:10]2[C:15](=[CH:14][CH:13]=[CH:12][CH:11]=2)[CH:7]([C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)[CH2:8]1

参加物

6

反応物 4

HCID 887MethanolHCID 11430Potassium CarbonateHCID 981461-Indanone, 3-phenyl-HCID 443297Hydroxyamine hydrochloride

生成物 1

HCID 731839393-Phenyl-1-indanone oxime

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

A mixture of 3-phenylindan-1-one (80 g), methanol (935 ml), water (90 ml), potassium carbonate (103.8 g), and hydroxylamine HCl (104.3 g) was heated at reflux for 16 hours, then poured into ice-water: the title compound was filtered, washed with water, with a small portion of ether, then dried in air. Yield: 74.7 g; m.p. 133°-139°.

後処理

  1. temperaturewas heated
  2. temperatureat reflux for 16 hours
  3. filtrationthe title compound was filtered
  4. washwashed with water, with a small portion of ether
  5. customdried in air

出典と根拠

ORDレコード
ord-06804961a4a94f6fab538831a07fec43
出典データセット
uspto-grants-1985_10
特許番号
US04548946

関連ノート

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