4-Phenyl-3-Buten-2-one → 4-Phenylbut-3-en-2-ol

HRID 467284

反応式

HRID 467284 の反応式
[CH:1](=[CH:8][C:9](=[O:11])[CH3:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C1C=CC(P(C2C=CC3C(=CC=CC=3)C=2C2C3C(=CC=CC=3)C=CC=2P(C2C=CC=CC=2)C2C=CC=CC=2)C2C=CC=CC=2)=CC=1.F[B-](F)(F)F>>[C:2]1([CH:1]=[CH:8][CH:9]([OH:11])[CH3:10])[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

参加物

4

反応物 3

HCID 159094-Phenyl-3-Buten-2-oneHCID 26255TetrafluoroborateHCID 634876Binap, (A+-)-

生成物 1

HCID 151724-Phenylbut-3-en-2-ol収率 26.4%

実験手順

In a 100 ml stainless steel autoclave were charged 5 g (34.2 mmole) of benzalacetone and 0.204 g (0.171 mmole) of ##STR25## ((+)-BINAP)}BF4 synthesized in Example 1, and the mixture was allowed to react in the same manner as in Example 12 to obtain 1.34 g of 4-phenyl-3-buten-2ol having a purity of 70% and an optical purity of 70.3 %ee at a conversion of 26.7%.

後処理

  1. customto react in the same manner as in Example 12

出典と根拠

ORDレコード
ord-cb472aa881234584844ecbe81012847b
出典データセット
uspto-grants-1992_10
特許番号
US05159093

関連ノート

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