Methanethiol → Ethyl 2-[(methylsulfanyl)methyl]prop-2-enoate
反応式
[CH3:1][SH:2].[Na].[CH2:4]([O:6][C:7](=[O:12])[C:8]([CH2:10]Br)=[CH2:9])[CH3:5]>C(O)C.O>[CH2:4]([O:6][C:7](=[O:12])[C:8]([CH2:10][S:2][CH3:1])=[CH2:9])[CH3:5]参加物
6
実験手順
A solution of methylmercaptan (4.8 g.) and sodium (2.3 g.) in absolute ethanol (75 ml.) is added dropwise to a solution of ethyl-2-bromomethylacrylate (19.3 g.) in ethanol (25 ml.). After two hours, it is diluted with water (400 ml.) and extracted with methylene chloride. The organic layer is dried and concentrated to dryness in vacuo to yield ethyl-2-methylthiomethylacrylate.
後処理
- extractionextracted with methylene chloride
- customThe organic layer is dried
- concentrationconcentrated to dryness in vacuo
出典と根拠
- ORDレコード
- ord-ef169ab13b9c4ed390f40d30a51c76c2
- 出典データセット
- uspto-grants-1979_11
- 特許番号
- US04175199
反応ノート
読み込み中…