2,3-Dihydroxybutanedioic Acid → 1-Acetyl-4-methylpiperazine

HRID 476855ノート

反応式

HRID 476855 の反応式
[CH3:1][N:2]1[CH2:7][CH2:6][NH:5][CH2:4][CH2:3]1.[C:8](O)(=O)[CH:9](C(C(O)=O)O)[OH:10]>>[CH3:1][N:2]1[CH2:7][CH2:6][N:5]([C:9](=[O:10])[CH3:8])[CH2:4][CH2:3]1

参加物

3

反応物 2

HCID 8752,3-Dihydroxybutanedioic AcidHCID 531671-Methylpiperazine

生成物 1

HCID 5507581-Acetyl-4-methylpiperazine収率 38%

実験手順

2-(2,3-Dihydro-2-oxo-3-phenyl-5-benzofuranyl)-1-(4-methylpiperazinyl-1-oxoethane was prepared according to the process described in Example 3, but using 4-methylpiperazine in Stage C. The latter compound was dissolved in a solution of DL-tartaric acid to form the corresponding salt, and then recrystallized in ethyl ether.

後処理

  1. customto form the corresponding salt
  2. customrecrystallized in ethyl ether

出典と根拠

ORDレコード
ord-09e7a41ec6654d729fc289e12b298cdb
出典データセット
uspto-grants-1989_12
特許番号
US04886799

反応ノート

読み込み中…