Methyl Salicylate → Trimethylolethane salicylate

反応式

[C:1]([O:10]CC(CO)O)(=[O:9])[C:2]1[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=1)[OH:4].[CH2:16]([C:18]([CH2:22][OH:23])([CH2:20][OH:21])[CH3:19])[OH:17].C(OC)(=O)C1C(=CC=CC=1)O.C[O-].[Na+]>>[C:1]([OH:10])(=[O:9])[C:2]1[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=1)[OH:4].[CH2:16]([C:18]([CH2:22][OH:23])([CH2:20][OH:21])[CH3:19])[OH:17]

参加物

反応物 4

HCID 4133Methyl Salicylate2 回

HCID 6502Trimethylolethane

HCID 38493182,3-Dihydroxypropyl salicylate

HCID 10942334Sodium Methoxide

生成物 1

HCID 70390081Trimethylolethane salicylate

実験手順

Trimethylolethane salicylate was prepared by the method described in Example 1 for the preparation of glycerol salicylate except that the reactants were trimethylolethane (60.1 g; 0.5 moles), methyl salicylate (119.7 g; 0.788 moles), sodium methoxide (0.82 g; 0.015 moles). The final methyl salicylate level was 10.0%.