Thiamine Hydrochloride → thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methyl-, salt with 1,2,3,4-tetrahydro-2-methyl-1,4-dioxo-2-naphthalenesulfonic acid (1:1), mono(1,2,3,4-tetrahydro-2-methyl-1,4-dioxo-2-naphthalenesulfonate) (salt)

HRID 482970

反応式

HRID 482970 の反応式
[CH3:1][C:2]1[N+:6]([CH2:7][C:8]2[CH:9]=[N:10][C:11]([CH3:15])=[N:12][C:13]=2[NH2:14])=[CH:5][S:4][C:3]=1[CH2:16][CH2:17][OH:18].Cl.[Cl-].[CH3:21][C:22]1([S:34]([O-:37])(=[O:36])=[O:35])[C:32](=[O:33])[C:31]2[C:26](=[CH:27][CH:28]=[CH:29][CH:30]=2)[C:24](=[O:25])[CH2:23]1.[Na+]>O>[CH3:21][C:22]1([S:34]([OH:37])(=[O:36])=[O:35])[C:32](=[O:33])[C:31]2[C:26](=[CH:27][CH:28]=[CH:29][CH:30]=2)[C:24](=[O:25])[CH2:23]1.[CH3:1][C:2]1[N+:6]([CH2:7][C:8]2[CH:9]=[N:10][C:11]([CH3:15])=[N:12][C:13]=2[NH2:14])=[CH:5][S:4][C:3]=1[CH2:16][CH2:17][OH:18]

参加物

4

反応物 2

HCID 6202Thiamine HydrochlorideHCID 23665888Menadione Sodium Bisulfite

生成物 1

HCID 121232542thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methyl-, salt with 1,2,3,4-tetrahydro-2-methyl-1,4-dioxo-2-naphthalenesulfonic acid (1:1), mono(1,2,3,4-tetrahydro-2-methyl-1,4-dioxo-2-naphthalenesulfonate) (salt)

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

25 g of thiamine hydrochloride (vitamin B1) was dissolved in 50 g of water; to said solution of 25 g of powdery sodium menadione bisulfite was added within about half an hour. After half an hour of agitation, the reaction mass became opalescent and the adduct began to precipitate. After an hour, the precipitate was filtered, washed and dried. 25 g of a white product having the following analysis was obtained.

後処理

  1. additionwas added within about half an hour
  2. waitAfter half an hour of agitation
  3. customto precipitate
  4. waitAfter an hour
  5. filtrationthe precipitate was filtered
  6. washwashed
  7. customdried
  8. customwas obtained

出典と根拠

ORDレコード
ord-a76a9e7bad3d40479e682b9c4056a987
出典データセット
uspto-grants-1986_03
特許番号
US04577019

関連ノート

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