Thionyl Chloride → 2-(7-Methoxynaphthalen-1-yl)acetyl chloride
反応式
[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([CH:7]=[CH:8][CH:9]=[C:10]2[CH2:13][C:14]([OH:16])=O)=[CH:5][CH:4]=1.S(Cl)([Cl:19])=O>C(Cl)(Cl)Cl>[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([CH:7]=[CH:8][CH:9]=[C:10]2[CH2:13][C:14]([Cl:19])=[O:16])=[CH:5][CH:4]=1参加物
4
実験手順
The (7-methoxynaphth-1-yl)acetic acid obtained above is dissolved by heating in 300 ml of chloroform. The mixture is heated under reflux, and then thionyl chloride is added dropwise. The mixture is refluxed for two hours and evaporated to dryness. An oil is obtained which crystallizes on cooling. The residue obtained is used as such in the following stage.
後処理
- dissolutionabove is dissolved
- temperatureThe mixture is heated
- temperatureunder reflux
- temperatureThe mixture is refluxed for two hours
- customevaporated to dryness
- customAn oil is obtained which
- customcrystallizes
- temperatureon cooling
- customThe residue obtained
出典と根拠
- ORDレコード
- ord-a5644afb33d14df0ac29383062107646
- 出典データセット
- uspto-grants-1993_07
- 特許番号
- US05225442
反応ノート
読み込み中…