Butylamine → n-Butyl-2,2,6,6-tetramethyl-4-piperidinamine

HRID 484934

反応式

HRID 484934 の反応式
[CH3:1][C:2]1([CH3:11])[CH2:7][C:6](=O)[CH2:5][C:4]([CH3:10])([CH3:9])[NH:3]1.[CH2:12]([NH2:16])[CH2:13][CH2:14][CH3:15]>CO.[Pt]=O>[CH2:12]([NH:16][CH:6]1[CH2:7][C:2]([CH3:11])([CH3:1])[NH:3][C:4]([CH3:10])([CH3:9])[CH2:5]1)[CH2:13][CH2:14][CH3:15]

参加物

5

反応物 2

HCID 8007ButylamineHCID 132202,2,6,6-Tetramethyl-4-piperidone

生成物 1

HCID 118285n-Butyl-2,2,6,6-tetramethyl-4-piperidinamine

試薬・触媒・溶媒 2

HCID 82844Platinum oxide (PtO)触媒HCID 887Methanol溶媒

実験手順

2.0 g of platinum oxide were added to a solution of 155 g of 2,2,6,6-tetramethyl-4-piperidone and 80 g of butylamine in 300 ml of methanol. The resulting mixture was then hydrogenated under a hydrogen atmosphere in a Parr hydrogenation apparatus at room temperature for 5 hours. After completion of the reaction, the platinum catalyst was filtered off and the solvent was distilled from the filtrate under reduced pressure. The residue was purified by vacuum distillation, to give the desired product as an oil, boiling at 100°-101° C./5 mmHg (667 Pascals).

後処理

  1. customAfter completion of the reaction
  2. filtrationthe platinum catalyst was filtered off
  3. distillationthe solvent was distilled from the filtrate under reduced pressure
  4. distillationThe residue was purified by vacuum distillation

出典と根拠

ORDレコード
ord-929b6e37381541248af7dca6487180fd
出典データセット
uspto-grants-1985_08
特許番号
US04533688

関連ノート

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