Pyridine → 3-Amino-5-[3-(pentylthio)propylthio]-1,2,4-triazole
反応式
[CH2:1]([S:6][CH2:7][CH2:8][CH2:9]Cl)[CH2:2][CH2:3][CH2:4][CH3:5].[NH2:11][C:12]1[N:16]=[C:15]([SH:17])[NH:14][N:13]=1.N1C=CC=CC=1.NC1N=C(SCCSCCSCCCCCC)NN=1>C(#N)C.O>[NH2:11][C:12]1[N:16]=[C:15]([S:17][CH2:9][CH2:8][CH2:7][S:6][CH2:1][CH2:2][CH2:3][CH2:4][CH3:5])[NH:14][N:13]=1参加物
7
実験手順
Compound 9 was prepared from a mixture of 3-chloropropyl pentyl sulfide, 3-amino-5-mercapto-1,2,4-triazole and pyridine in acetonitrile, as described previously for Compound 12. The reaction mixture was poured into water and extracted with CH2Cl2. The extracts were washed with water and brine, dried over MgSO4, and concentrated under vacuum to provide Compound 9 in 71% yield.
後処理
- extractionextracted with CH2Cl2
- washThe extracts were washed with water and brine
- dry with materialdried over MgSO4
- concentrationconcentrated under vacuum
出典と根拠
- ORDレコード
- ord-e6c26a24494a483faac30057276f6133
- 出典データセット
- uspto-grants-1994_03
- 特許番号
- US05292627
反応ノート
読み込み中…