HCID 67530783、化合物 → HCID 67529444、化合物

HRID 499022

反応式

HRID 499022 の反応式
[NH:1]1[C:5]([C:6]2[C:14]3[C:9](=[CH:10][C:11]([CH3:17])=[C:12]([O:15][CH3:16])[CH:13]=3)[CH2:8][CH:7]=2)=[CH:4][N:3]=[CH:2]1>[Pd].C(O)C.O.[Pt]=O>[NH:1]1[C:5]([CH:6]2[C:14]3[C:9](=[CH:10][C:11]([CH3:17])=[C:12]([O:15][CH3:16])[CH:13]=3)[CH2:8][CH2:7]2)=[CH:4][N:3]=[CH:2]1

参加物

5

反応物 1

HCID 67530783HCID 67530783、化合物

生成物 1

HCID 67529444HCID 67529444、化合物

試薬・触媒・溶媒 3

HCID 23938Palladium触媒HCID 86587499Platinum oxide monohydrate触媒HCID 702Ethanol溶媒

実験手順

This compound was prepared in a manner analogous to that of Step E of Example 1, by the hydrogenation of 0.5 gram (0.0022 mole) of 3-(imidazol-5-yl)-5-methoxy-6-methylindene (viii) in the presence of 0.1 gram (catalyst) of 10% palladium on carbon and 0.1 gram (catalyst) of platinum oxide hydrate in 40 mL of ethanol. The yield of subject compound was 0.42 gram, mp 68-70° C. The NMR spectrum was consistent with the proposed structure.

後処理

  1. customThis compound was prepared in a manner analogous to that of Step E of Example 1

出典と根拠

ORDレコード
ord-ddef700dccce4e6487c6d9dacbbe1683
出典データセット
uspto-grants-2010_08
特許番号
US07767667B2

関連ノート

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