Tetrahydrofuran → (1,1'-Biphenyl)-3-carboxylic acid
反応式
[C:1]1([C:7]2[CH:8]=[C:9]([CH:14]=[CH:15][CH:16]=2)[C:10]([O:12]C)=[O:11])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[OH-].[Na+].O1CCCC1>CO>[C:1]1([C:7]2[CH:8]=[C:9]([CH:14]=[CH:15][CH:16]=2)[C:10]([OH:12])=[O:11])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1参加物
5
実験手順
0.90 g of methyl 3-phenylbenzoate was fed into 20 ml of a solvent mixture of aqueous solution of 2 M of sodium hydroxide, tetrahydrofuran and methanol (4/2/1) to conduct the reaction at 70° C. for 2 hours. The solvent was evaporated, and the residue was fed into 3 M of hydrochloric acid. The precipitate thus formed was taken by the filtration and dried to obtain the title compound in the form of white crystals.
後処理
- customthe reaction at 70° C. for 2 hours
- customThe solvent was evaporated
- customThe precipitate thus formed
- filtrationwas taken by the filtration
- customdried
出典と根拠
- ORDレコード
- ord-b6d106859ae042a0be8637cd84cd0072
- 出典データセット
- uspto-grants-2004_03
- 特許番号
- US06710056B2
反応ノート
読み込み中…