m-Chloroperbenzoic acid → 2-(2-Pyridylmethyl)-1H-isoindole-1,3(2H)-dione N-oxide
反応式
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[CH2:7][N:8]1[C:16](=[O:17])[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[C:9]1=[O:18].ClC1C=CC=C(C(OO)=[O:27])C=1>C(Cl)(Cl)Cl>[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[CH2:7][N+:8]1([O-:27])[C:16](=[O:17])[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[C:9]1=[O:18]参加物
4
実験手順
2-(2-Pyridylmethyl)-1H-isoindole-1,3(2H)-dione (7.5 g, 32 mmol) and 3-chloroperbenzoic acid (77%, 14.3 g, 64 mmol) were dissolved in chloroform (250 ml), and the mixture was stirred at room temperature for 20 hrs. The solvent was evaporated, and the residue was washed with ethyl acetate to give the titled compound (8.0 g, 99%) as white crystals.
後処理
- customThe solvent was evaporated
- washthe residue was washed with ethyl acetate
出典と根拠
- ORDレコード
- ord-6a540c640f6a44cea2dc197dab134bc1
- 出典データセット
- uspto-grants-2010_08
- 特許番号
- US07767665B2
反応ノート
読み込み中…