Diethylene Glycol Monomethyl Ether → HCID 131728281、化合物

HRID 502487ノート

反応式

HRID 502487 の反応式
[CH3:1][C@@H:2]1[O:9]C(=O)[C@H](C)[O:5][C:3]1=[O:4].[CH3:11][O:12][CH2:13][CH2:14][O:15][CH2:16][CH2:17][OH:18].[C:19]([OH:24])(=[O:23])[C@H:20]([CH3:22])[OH:21].C[C@H]1OC(=O)[C@@H](C)OC1=O.[CH3:35][O:36][CH2:37][CH2:38][O:39][CH2:40][CH2:41][OH:42].CCCCC(C([O-])=O)CC.CCCCC(C([O-])=O)CC.[Sn+2]>>[CH3:11][O:12][CH2:13][CH2:14][O:15][CH2:16][CH2:17][OH:18].[C:3]([OH:5])(=[O:4])[C@H:2]([CH3:1])[OH:9].[CH3:35][O:36][CH2:37][CH2:38][O:39][CH2:40][CH2:41][OH:42].[C:19]([OH:24])(=[O:23])[C@@H:20]([CH3:22])[OH:21]

参加物

7

反応物 5

HCID 8134Diethylene Glycol Monomethyl EtherHCID 93182-ethylhexanoic acid tin(II) saltHCID 107983Lactide, L-HCID 5325924D,D-DilactideHCID 131728281HCID 131728281、化合物

生成物 2

HCID 131728281HCID 131728281、化合物HCID 131728282HCID 131728282、化合物

実験手順

Ringopening polymerization of lactide (L-lactide for system (A) and D-lactide for system B, each 5 g) was carried out using 2-(2-methoxyethoxy)ethanol (MEE, 0.556 g) as an initiator, and stannous octoate (0.093 g) as the catalyst. The polymerization was carried out in the melt at 130° C. for four hours to yield MEE-L-lactic acid oligomer (A) and MEE-D-lactic acid oligomer (B). FIG. 1 shows the reaction scheme for the synthesis of dex-lactate (8), in which the DP is the degree of polymerization and DS is the degree of substitution (number of lactic acid oligomers per 100 glucopyranose units of dextran.

出典と根拠

ORDレコード
ord-29aa9c7e73964c1c965d400d8b79f949
出典データセット
uspto-grants-2010_08
特許番号
US07776359B1

反応ノート

読み込み中…