Sodium hydride → 1-(2-Thienyl)cyclopent-3-ene-1-carbonitrile

HRID 502949

反応式

HRID 502949 の反応式
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH2:6][C:7]#[N:8].[H-].[Na+]>CN(C=O)C>[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]1([C:7]#[N:8])[CH2:4][CH:3]=[CH:2][CH2:6]1

参加物

4

反応物 2

HCID 24758Sodium hydrideHCID 728802-Thienylacetonitrile

生成物 1

HCID 653530801-(2-Thienyl)cyclopent-3-ene-1-carbonitrile

試薬・触媒・溶媒 1

HCID 6228Dimethylformamide溶媒

実験手順

Thiophene-2-acetonitrile and 1,4-dichloride-2-butene were added to a DMF solution of sodium hydride washed with hexane and the whole was reacted at room temperature to obtain 1-(2-thienyl)cyclopent-3-ene-1-carbonitrile.

後処理

  1. washwashed with hexane
  2. customthe whole was reacted at room temperature

出典と根拠

ORDレコード
ord-8008992ec5f640278445eefa7cfdca24
出典データセット
uspto-grants-2010_08
特許番号
US07776897B2

関連ノート

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