Trifluoroacetic acid → Diethyl (4-{[4-{[2-(methylcarbamoyl)phenyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}benzyl)phosphonate

反応式

Cl[C:2]1[N:7]=[C:6](Cl)[C:5]([C:9]([F:12])([F:11])[F:10])=[CH:4][N:3]=1.[NH2:13][C:14]1[CH:23]=[CH:22][CH:21]=[CH:20][C:15]=1[C:16]([NH:18][CH3:19])=[O:17].C(N(C(C)C)CC)(C)C.ClC1N=C(NC2C=CC=CC=2C(NC)=O)C(C(F)(F)F)=CN=1.ClC1C(C(F)(F)F)=CN=C(NC2C=CC=CC=2C(NC)=O)N=1.[NH2:77][C:78]1[CH:92]=[CH:91][C:81]([CH2:82][P:83](=[O:90])([O:87][CH2:88][CH3:89])[O:84][CH2:85][CH3:86])=[CH:80][CH:79]=1.C(O)(C(F)(F)F)=O>C(Cl)Cl>[CH3:19][NH:18][C:16]([C:15]1[CH:20]=[CH:21][CH:22]=[CH:23][C:14]=1[NH:13][C:6]1[C:5]([C:9]([F:12])([F:11])[F:10])=[CH:4][N:3]=[C:2]([NH:77][C:78]2[CH:79]=[CH:80][C:81]([CH2:82][P:83](=[O:90])([O:84][CH2:85][CH3:86])[O:87][CH2:88][CH3:89])=[CH:91][CH:92]=2)[N:7]=1)=[O:17]