Oxalyl chloride → 2-(Ethylthio)benzoyl chloride

HRID 533677ノート

反応式

HRID 533677 の反応式
[CH2:1]([S:3][C:4]1[CH:12]=[CH:11][CH:10]=[CH:9][C:5]=1[C:6](O)=[O:7])[CH3:2].C(Cl)(=O)C([Cl:16])=O>CN(C=O)C.C(Cl)(Cl)Cl>[CH2:1]([S:3][C:4]1[CH:12]=[CH:11][CH:10]=[CH:9][C:5]=1[C:6]([Cl:16])=[O:7])[CH3:2]

参加物

5

反応物 2

HCID 65578Oxalyl chlorideHCID 4257582-(Ethylsulfanyl)benzoic acid

生成物 1

HCID 148531752-(Ethylthio)benzoyl chloride収率 100%

試薬・触媒・溶媒 2

HCID 6228Dimethylformamide触媒HCID 6212Chloroform溶媒

実験手順

To a mixture of 2-ethylsulfanylbenzoic acid (9.11 g), chloroform (100 ml), and oxalyl chloride (9.72 g), DMF (2 drops) was added, and stirred at room temperature for 6 hours. The reaction mixture was concentrated under reduced pressure to give 10.03 g of 2-ethylsulfanylbenzoic acid chloride (Compound (1H)-241).

後処理

  1. additionwas added
  2. concentrationThe reaction mixture was concentrated under reduced pressure

出典と根拠

ORDレコード
ord-8d4b998dbd6649999510899b31db47f7
出典データセット
uspto-grants-2014_10
特許番号
US08853238B2

反応ノート

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