N-bromobutanimide → 2-(Bromomethyl)-3-chloro-1,1'-biphenyl

HRID 544674

反応式

HRID 544674 の反応式
[Cl:1][C:2]1[C:3]([CH3:14])=[C:4]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[CH:5]=[CH:6][CH:7]=1.[Br:15]N1C(=O)CCC1=O>C(Cl)(Cl)(Cl)Cl>[Br:15][CH2:14][C:3]1[C:2]([Cl:1])=[CH:7][CH:6]=[CH:5][C:4]=1[C:8]1[CH:9]=[CH:10][CH:11]=[CH:12][CH:13]=1

参加物

4

反応物 2

HCID 67184N-bromobutanimideHCID 46018323-Chloro-2-methylbiphenyl

生成物 1

HCID 133207002-(Bromomethyl)-3-chloro-1,1'-biphenyl

試薬・触媒・溶媒 1

HCID 5943Carbon Tetrachloride溶媒

実験手順

A mixture of 3-chloro-2-methyl[1,1'-biphenyl] (10.4 grams, 0.051 mole) and N-bromosuccinimide (9.2 grams, 0.052 mole) in carbon tetrachloride (150 ml) was heated and irradiated with an infrared lamp for two hours. The mixture was cooled and filtered. The filtrate was evaporated under reduced pressure to give a quantitative yield of 2-bromomethyl-3-chloro[1,1'-biphenyl] as a yellow oil.

後処理

  1. temperaturewas heated
  2. customirradiated with an infrared lamp for two hours
  3. temperatureThe mixture was cooled
  4. filtrationfiltered
  5. customThe filtrate was evaporated under reduced pressure

出典と根拠

ORDレコード
ord-c6f05b515ffa4cb4b7c949cce15d8276
出典データセット
uspto-grants-1984_05
特許番号
US04451484

関連ノート

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