Methyl iodide → 1-(3,4-Dihydroquinolin-1(2H)-ylcarbonyl)-3-methyl-1H-imidazol-3-ium Iodide

HRID 551790ノート

反応式

HRID 551790 の反応式
[N:1]1([C:6]([N:8]2[C:17]3[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=3)[CH2:11][CH2:10][CH2:9]2)=[O:7])[CH:5]=[CH:4][N:3]=[CH:2]1.[I:18][CH3:19]>C(#N)C>[I-:18].[N:8]1([C:6]([N:1]2[CH:5]=[CH:4][N+:3]([CH3:19])=[CH:2]2)=[O:7])[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)[CH2:11][CH2:10][CH2:9]1

参加物

4

反応物 2

HCID 6328Methyl iodideHCID 109552981-(1H-imidazol-1-ylcarbonyl)-1,2,3,4-tetrahydroquinoline

生成物 1

HCID 109595761-(3,4-Dihydroquinolin-1(2H)-ylcarbonyl)-3-methyl-1H-imidazol-3-ium Iodide

試薬・触媒・溶媒 1

HCID 6342Acetonitrile溶媒

実験手順

13.3 g of 1-(1H-imidazol-1-ylcarbonyl)-1,2,3,4-tetrahydroquinoline, 133 ml of acetonitrile and 14.6 ml of iodomethane are introduced into a 500 ml round-bottomed flask. The reaction mixture is stirred for 20 h and then the solvent is evaporated under reduced pressure to result in 23 g of 1-(3,4-dihydroquinolin-1(2H)-ylcarbonyl)-3-methyl-1H-imidazol-3-ium iodide.

後処理

  1. customthe solvent is evaporated under reduced pressure
  2. customto result in 23 g of 1-(3,4-dihydroquinolin-1(2H)-ylcarbonyl)-3-methyl-1H-imidazol-3-ium iodide

出典と根拠

ORDレコード
ord-7034e0e12f3046a29c5136e11fdd46bb
出典データセット
uspto-grants-2011_05
特許番号
US07947834B2

反応ノート

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