Water → 2,4,6-Tris(bromomethyl)nitrobenzene
反応式
[Br:1][CH2:2][C:3]1[CH:8]=[C:7]([CH2:9][Br:10])[CH:6]=[C:5]([CH2:11][Br:12])[CH:4]=1.F[B-](F)(F)F.[O:18]=[N+:19]=[O:20].O>CC#N>[Br:1][CH2:2][C:3]1[CH:4]=[C:5]([CH2:11][Br:12])[CH:6]=[C:7]([CH2:9][Br:10])[C:8]=1[N+:19]([O-:20])=[O:18]参加物
5
実験手順
To a solution of 5 g (0.014 mole) of the tribromide 8 in 100 ml of CH3CN was added, at room temperature and under argon atmosphere, in a dropwise fashion 3.72 g (0.028 mole) of nitronium tetrafluoroborate in 200 ml of CH3CN. The solution was then stirred for 20 minutes longer, poured into water and the mixture extracted with CH2Cl2. The CH2Cl2 extracts were washed with 10% NaHCO3, dried (Na2SO4) and solvents removed to afford 4.86 g (86%) of the desired nitro compound 27: NMR (CDCl3) 4.5 (s,6,--CH2Br), 7.55 (s,--C6H2).
後処理
- extractionthe mixture extracted with CH2Cl2
- washThe CH2Cl2 extracts were washed with 10% NaHCO3
- dry with materialdried (Na2SO4) and solvents
- customremoved
出典と根拠
- ORDレコード
- ord-728658d230cb49b7815fa4f092792817
- 出典データセット
- uspto-grants-1993_09
- 特許番号
- US05245038
反応ノート
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