反応式
[C:1]1([NH:7][C:8]2[CH:16]=[CH:15][CH:14]=[CH:13][C:9]=2[C:10]([NH2:12])=[O:11])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:17](Cl)(=O)[CH2:18][CH3:19].C(=O)(O)[O-].[Na+]>ClC(Cl)Cl>[CH2:18]([C:19]1[N:7]([C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)[C:8]2[C:9]([C:10](=[O:11])[N:12]=1)=[CH:13][CH:14]=[CH:15][CH:16]=2)[CH3:17]参加物
5
反応条件
- 温度
- 0 °C
実験手順
2.0 g (9.42 mmol) 2-phenylamino-benzamide were dissolved in 30 ml trichloromethane the solution was cooled to 0° C., and 2.61 g (2.44 ml, 28.2 mmol) propionyl chloride was added slowly. The mixture was boiled for 90 minutes and afterwards neutralized with a saturated sodium bicarbonate solution. After evaporation the substance was crystallized from isopropanol.
後処理
- customAfter evaporation the substance
- customwas crystallized from isopropanol
出典と根拠
- ORDレコード
- ord-3a03597141834694b183180e548982e9
- 出典データセット
- uspto-grants-2011_11
- 特許番号
- US08058431B2
関連ノート
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