Triphosgene → 5,6-Dimethoxyisatoic anhydride
反応式
[NH2:1][C:2]1[C:7]([C:8]([OH:10])=[O:9])=[C:6]([O:11][CH3:12])[C:5]([O:13][CH3:14])=[CH:4][CH:3]=1.Cl[C:16](Cl)([O:18]C(=O)OC(Cl)(Cl)Cl)Cl>O1CCCC1>[CH3:12][O:11][C:6]1[C:7]2[C:8](=[O:10])[O:9][C:16](=[O:18])[NH:1][C:2]=2[CH:3]=[CH:4][C:5]=1[O:13][CH3:14]参加物
4
実験手順
10.0 g (50.7 mmol) 6-Amino-2,3-dimethoxy-benzoic acid were dissolved in 150 ml tetrahydrofuran, 6.52 g (22.0 mmol) triphosgene were added and the solution was refluxed for 3 h. After pouring on 400 ml of a ice/water mixture the precipitate was filtrated and rinsed with water and methanol.
後処理
- temperaturethe solution was refluxed for 3 h
- filtrationwas filtrated
- washrinsed with water and methanol
出典と根拠
- ORDレコード
- ord-7c2639eeec404c40a486bcc56b86cecf
- 出典データセット
- uspto-grants-2011_11
- 特許番号
- US08058431B2
反応ノート
読み込み中…