Phthalic Anhydride → 2-[4-(Diethylamino)-2-hydroxybenzoyl]benzoic acid

HRID 565077

反応式

HRID 565077 の反応式
[CH2:1]([N:3]([CH2:11][CH3:12])[C:4]1[CH:5]=[C:6]([OH:10])[CH:7]=[CH:8][CH:9]=1)[CH3:2].[C:13]1(=[O:23])[O:18][C:16](=[O:17])[C:15]2=[CH:19][CH:20]=[CH:21][CH:22]=[C:14]12>C1(C)C=CC=CC=1>[C:16]([C:15]1[CH:19]=[CH:20][CH:21]=[CH:22][C:14]=1[C:13]([C:7]1[CH:8]=[CH:9][C:4]([N:3]([CH2:1][CH3:2])[CH2:11][CH3:12])=[CH:5][C:6]=1[OH:10])=[O:23])([OH:18])=[O:17]

参加物

4

反応物 2

HCID 6811Phthalic AnhydrideHCID 70623-(Diethylamino)phenol

生成物 1

HCID 798782-[4-(Diethylamino)-2-hydroxybenzoyl]benzoic acid

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒

実験手順

2-(2′-Carboxybenzoyl)-5-diethylaminophenol was prepared as follows. A mixture of m-diethylaminophenol (1 mole) and phthalic anhydride (1.2 moles) was refluxed in toluene (2.0 L) for about 16 hours, cooled, and the resulting solid filtered, washed with toluene and dried to give 2-(2′-carboxybenzoyl)-5-diethylaminophenol in 70% yield.

後処理

  1. custom2-(2′-Carboxybenzoyl)-5-diethylaminophenol was prepared
  2. temperaturecooled
  3. filtrationthe resulting solid filtered
  4. washwashed with toluene
  5. customdried

出典と根拠

ORDレコード
ord-6101d14e85e44ff5aac0ecc59b3cd271
出典データセット
uspto-grants-2001_01
特許番号
US06169185A

関連ノート

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