Water → 5-Hydroxy-8H-9,11-dioxa-5-aza-benzo[de]anthracene4,6-dione
反応式
[CH:1]1[C:16]2[C:17]3[C:4]([C:5](=O)[O:6][C:7](=[O:18])[C:8]=3[CH:9]=[C:10]3[C:15]=2[O:14][CH2:13][O:12][CH2:11]3)=[CH:3][CH:2]=1.Cl.[NH2:21][OH:22].O>N1C=CC=CC=1>[OH:22][N:21]1[C:5](=[O:6])[C:4]2=[CH:3][CH:2]=[CH:1][C:16]3[C:17]2=[C:8]([CH:9]=[C:10]2[C:15]=3[O:14][CH2:13][O:12][CH2:11]2)[C:7]1=[O:18]参加物
5
実験手順
To a solution of 310 mg (1.21 mmol) of 8H-5,9,11-trioxabenzo[de]anthracene-4,6-dione (from Example T3) in 4 mL pyridine was added 260 mg (3.74 mmol) of hydroxylamine hydrochloride and the reaction mixture refluxed for 2 hours and poured into 50 mL water while hot. The precipitate was isolated, washed with water, and dried to yield 190 mg of the title compound, mp 314-315° C.
後処理
- temperaturethe reaction mixture refluxed for 2 hours
- customThe precipitate was isolated
- washwashed with water
- customdried
出典と根拠
- ORDレコード
- ord-e1e2c1165037471585205e8ebb6f0f33
- 出典データセット
- uspto-grants-2001_01
- 特許番号
- US06177423B1
反応ノート
読み込み中…