Diethylamine → N,N-diethyl-4-iodobenzamide

HRID 568871

反応式

HRID 568871 の反応式
[I:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](Cl)=[O:7])=[CH:4][CH:3]=1.[CH2:11]([NH:13][CH2:14][CH3:15])[CH3:12]>C(N(CC)CC)C>[CH2:11]([N:13]([CH2:14][CH3:15])[C:6](=[O:7])[C:5]1[CH:9]=[CH:10][C:2]([I:1])=[CH:3][CH:4]=1)[CH3:12]

参加物

4

反応物 2

HCID 8021DiethylamineHCID 743734-Iodobenzoyl chloride

生成物 1

HCID 875218N,N-diethyl-4-iodobenzamide収率 89.7%

試薬・触媒・溶媒 1

HCID 8471Triethylamine溶媒

実験手順

4-Iodobenzoyl chloride (10.0 g) was added portionwise to diethylamine (2.92 g) in triethylamine (40 ml) at 20°. The resulting slurry was stirred at room temperature for 1 h, diluted with ER (150 ml), filtered and evaporated to give the title compound as an orange solid (10.2 g) m.p. 68°-70°.

後処理

  1. additiondiluted with ER (150 ml)
  2. filtrationfiltered
  3. customevaporated

出典と根拠

ORDレコード
ord-887f5a3b3710439bad711194767794ab
出典データセット
uspto-grants-1988_03
特許番号
US04730008

関連ノート

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