Methyl iodide → Methyl 4-oxo-3-(prop-2-ynyl)-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carbimidothioate hydroiodide

HRID 570941ノート

反応式

HRID 570941 の反応式
[O:1]=[C:2]1[N:7]([CH2:8][C:9]#[CH:10])[N:6]=[N:5][C:4]2=[C:11]([C:14](=[S:16])[NH2:15])[N:12]=[CH:13][N:3]12.[I:17][CH3:18]>CC#N>[IH:17].[CH3:18][S:16][C:14]([C:11]1[N:12]=[CH:13][N:3]2[C:2](=[O:1])[N:7]([CH2:8][C:9]#[CH:10])[N:6]=[N:5][C:4]=12)=[NH:15]

参加物

4

反応物 2

HCID 6328Methyl iodideHCID 498691414-Oxo-3-(prop-2-ynyl)-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carbothioamide

生成物 1

HCID 86663789Methyl 4-oxo-3-(prop-2-ynyl)-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carbimidothioate hydroiodide

試薬・触媒・溶媒 1

HCID 6342Acetonitrile溶媒

実験手順

4-oxo-3-(prop-2-ynyl)-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carbothioamide (0.323 g; 0.86 mmol) was dissolved in dry MeCN (1 mL) and iodomethane (1.220 g; 8.6 mmol) was added and the reaction mixture stirred at room temperature overnight.

出典と根拠

ORDレコード
ord-c9eedfe3fe944eee8221b6d9f5b6b56a
出典データセット
uspto-grants-2015_05
特許番号
US09024018B2

反応ノート

読み込み中…