Formaldehyde → 3-[(3-Hydroxypropyl)amino]propanenitrile

反応式

[NH2:1][CH2:2][CH2:3][CH2:4][OH:5].[C:6](#[N:9])[CH:7]=[CH2:8].C=O.C#N.C=O.C#N.S([O-])(O)=O>>[C:6]([CH2:7][CH2:8][NH:1][CH2:2][CH2:3][CH2:4][OH:5])#[N:9]

参加物

反応物 6

HCID 712Formaldehyde

HCID 768Hydrogen Cyanide

HCID 7855Acrylonitrile

HCID 90863-Amino-1-propanol

HCID 104748Bisulfite

HCID 86742226Formaldehyde hydrocyanic acid

生成物 1

HCID 135569403-[(3-Hydroxypropyl)amino]propanenitrile

実験手順

75 grams (1 mole) of 3-amino-propanol were treated with 53 grams (1 mole) of acrylonitrile within one hour at 25° C. The mixture was allowed to react further for 1 hour at 40° C. The thus obtained reaction product (128 grams) was directly reacted further with formaldehyde/hydrocyanic acid or formaldehyde/alkali salt of hydrocyanic acid in the presence of alkali hydrogen sulfite.

後処理

customto react further for 1 hour at 40° C

出典と根拠

ORDレコード: ord-0280d27fa4724f99931795ea94bea3bf
出典データセット: uspto-grants-1988_06
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04751298

反応ノート

読み込み中…