O-Toluidine → 1-Propyl-3-(O-tolyl)urea
反応式
[NH2:1][C:2]1[C:3]([CH3:8])=[CH:4][CH:5]=[CH:6][CH:7]=1.[CH2:9]([N:12]=[C:13]=[O:14])[CH2:10][CH3:11]>C1(C)C=CC=CC=1>[CH3:8][C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=1[NH:1][C:13]([NH:12][CH2:9][CH2:10][CH3:11])=[O:14]参加物
4
実験手順
2-Toluidine (32.1 g) was dissolved in toluene (500 ml) and propyl isocyanate (25.2 g) was added in one portion with stirring. The mixture was stirred for 1 h and then allowed to stand at room temperature for 6 h. The solid was collected by filtration and washed with toluene to provide the title compound (36.5 g).
後処理
- stirringThe mixture was stirred for 1 h
- filtrationThe solid was collected by filtration
- washwashed with toluene
出典と根拠
- ORDレコード
- ord-d5d2a29526984bf8bd2400d670577b4a
- 出典データセット
- uspto-grants-1999_07
- 特許番号
- US05919789
反応ノート
読み込み中…