HCID 10012515、化合物 → HCID 22342827、化合物
反応式
[CH3:1][N:2]1[CH:6]=[C:5](/[CH:7]=[CH:8]/[C:9]([O:11][CH2:12][CH3:13])=[O:10])[N:4]=[CH:3]1>O1CCCC1.[Pd]>[CH3:1][N:2]1[CH:6]=[C:5]([CH2:7][CH2:8][C:9]([O:11][CH2:12][CH3:13])=[O:10])[N:4]=[CH:3]1参加物
4
実験手順
A solution of ethyl (E)-3-(1-methyl-1H-imidazol-4-yl)acrylate (2.5 g) in tetrahydrofuran (100 ml) was hydrogenated over 10% palladium activated carbon (0.2 g) at room temperature under 2 atmospheric pressure. After removal of catalyst by filtration through Celite pad, the filtrate was concentrated under reduced pressure to give ethyl 3-(1-methyl-1H-imidazol-4-yl)propionate (2.63 g).
後処理
- customAfter removal of catalyst
- filtrationby filtration through Celite pad
- concentrationthe filtrate was concentrated under reduced pressure
出典と根拠
- ORDレコード
- ord-54437d5a158441fa907f050c1ce2a195
- 出典データセット
- uspto-grants-2005_08
- 特許番号
- US06924278B2
反応ノート
読み込み中…