Dicyclohexylamine → 2-Butyloctanoyl chloride
反応式
C1(NC2CCCCC2)CCCCC1.[CH2:14]([CH:18]([CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27])[C:19](O)=[O:20])[CH2:15][CH2:16][CH3:17].S(Cl)([Cl:30])=O>ClCCl.C(OCC)C>[CH2:14]([CH:18]([CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH3:27])[C:19]([Cl:30])=[O:20])[CH2:15][CH2:16][CH3:17]参加物
6
実験手順
500 μl (2.5 mmol) of dicyclohexylamine are added to 500 mg (2.5 mmol) of 2-butyloctanoic acid placed in 5 ml of dichloromethane, and the solution is stirred at room temperature for minutes. 200 μl (2.5 mmol) of thionyl chloride are then added and this mixture is stirred at room temperature for 2 hours. The reaction is diluted with ethyl ether. The precipitate is filtered off and rinsed with ethyl ether. Concentration of the filtrate gives the 2-butyloctanoyl chloride.
後処理
- stirringthis mixture is stirred at room temperature for 2 hours
- filtrationThe precipitate is filtered off
- washrinsed with ethyl ether
出典と根拠
- ORDレコード
- ord-9601ec8bb4c6491c9bb1c2911ace1e2b
- 出典データセット
- uspto-grants-2005_08
- 特許番号
- US06927228B2
反応ノート
読み込み中…