4-tert-Butylbenzaldehyde → Butyl-[6-(4-tert-butyl-phenyl)-2-methyl-imidazo[2,1-b]thiazol-5-yl]-amine
反応式
[CH3:1][C:2]1[S:6][C:5]([NH2:7])=[N:4][CH:3]=1.[CH2:8]([N+:12]#[C-:13])[CH2:9][CH2:10][CH3:11].[C:14]([C:18]1[CH:25]=[CH:24][C:21]([CH:22]=O)=[CH:20][CH:19]=1)([CH3:17])([CH3:16])[CH3:15]>Cl(O)(=O)(=O)=O>[CH2:8]([NH:12][C:13]1[N:4]2[C:5]([S:6][C:2]([CH3:1])=[CH:3]2)=[N:7][C:22]=1[C:21]1[CH:24]=[CH:25][C:18]([C:14]([CH3:17])([CH3:16])[CH3:15])=[CH:19][CH:20]=1)[CH2:9][CH2:10][CH3:11]参加物
5
実験手順
Compound 42 was prepared in accordance with the general synthesis instructions from 1.0 ml (0.1 mmol) 5-methyl-thiazol-2-yl-amine solution (0.1 M, MC), 0.575 ml (0.115 mmol) n-butylisonitrile solution (0.2 M, MC), 0.500 ml (0.15 mmol) 4-tert-butylbenzaldehyde solution (0.3 M, MC) and 10 μl perchloric acid (w 20%) in a substance library.