Methyl iodide → 3-Methylbenzoselenazolinone

HRID 5913

反応式

HRID 5913 の反応式
[Se:1]1(=[O:10])[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[CH:2]1.[Na].[CH3:12]I>O>[CH3:12][N:3]1[C:4]2[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=2[Se:1](=[O:10])[CH2:2]1

参加物

5

反応物 3

HCID 6328Methyl iodideHCID 5360545SodiumHCID 87879929Benzoselenazolinone

生成物 1

HCID 867472223-Methylbenzoselenazolinone

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

0.01 mol of benzoselenazolinone is introduced into a ground-necked round-bottomed flask containing 0.35 gram (0.015 gram-atom) of sodium dissolved in 50 l cm3 of absolute alcohol. 3.1 cm3 (0.05 mol) of methyl iodide are added dropwise and with stirring. After 12 hours, the solvent is evaporated off. The solid obtained is taken up with 30 to 40 cm3 of water and then extracted with chloroform. The chloroform phase is dried over calcium chloride and the solvent is then evaporated off under reduced pressure. The product is recrystallized in cyclohexane.

後処理

  1. customthe solvent is evaporated off
  2. customThe solid obtained
  3. extractionextracted with chloroform
  4. dry with materialThe chloroform phase is dried over calcium chloride
  5. customthe solvent is then evaporated off under reduced pressure
  6. customThe product is recrystallized in cyclohexane

出典と根拠

ORDレコード
ord-22b7b4af1b9c4b7eba64bdf1c4500578
出典データセット
uspto-grants-1993_09
特許番号
US05246951

関連ノート

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