Ammonia → 5-((2,2,2-Trifluoroacetamido)methyl)-2-chloro-4 methoxybenzamide
反応式
[F:1][C:2]([F:20])([F:19])[C:3]([NH:5][CH2:6][C:7]1[C:8]([O:17][CH3:18])=[CH:9][C:10]([Cl:16])=[C:11]([CH:15]=1)[C:12](O)=[O:13])=[O:4].C(Cl)(=O)C(Cl)=O.[NH3:27]>C1COCC1>[F:1][C:2]([F:20])([F:19])[C:3]([NH:5][CH2:6][C:7]1[C:8]([O:17][CH3:18])=[CH:9][C:10]([Cl:16])=[C:11]([CH:15]=1)[C:12]([NH2:27])=[O:13])=[O:4]参加物
5
実験手順
The title compound was prepared according to the procedure described in step-2 of Intermediate-26 by using 5-((2,2,2-trifluoroacetamido)methyl)-2-chloro-4-methoxybenzoic acid (1.0 g), oxalyl chloride (1.0 mL), THF (50 mL) and ammonia gas to afford 0.800 g of the desired product.
後処理
- customThe title compound was prepared
出典と根拠
- ORDレコード
- ord-e69c6750c6694d3c9d9b32d018d9e3df
- 出典データセット
- uspto-grants-2016_09
- 特許番号
- US09439890B2
反応ノート
読み込み中…