Sodium Carbonate → 4-(2-amino-5-(6-oxopiperidin-3-yl)pyridin-3-yl)-N-((S)-1-(3-chlorophenyl)-2-hydroxyethyl)-2-fluorobenzamide

反応式

[NH2:1][C:2]1[N:7]=[CH:6][C:5]([CH:8]2[CH2:13][NH:12][C:11](=[O:14])[CH2:10][CH2:9]2)=[CH:4][C:3]=1Br.[Cl:16][C:17]1[CH:18]=[C:19]([C@H:23]([NH:26][C:27]([C:29]2[CH:34]=[CH:33][C:32](B(O)O)=[CH:31][C:30]=2[F:38])=[O:28])[CH2:24][OH:25])[CH:20]=[CH:21][CH:22]=1.C([O-])([O-])=O.[Na+].[Na+].S([O-])([O-])(=O)=O.[Na+].[Na+]>C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.C1C=CC(P(C2C=CC=CC=2)[C-]2C=CC=C2)=CC=1.Cl[Pd]Cl.[Fe+2].COCCOC>[NH2:1][C:2]1[C:3]([C:32]2[CH:33]=[CH:34][C:29]([C:27]([NH:26][C@@H:23]([C:19]3[CH:20]=[CH:21][CH:22]=[C:17]([Cl:16])[CH:18]=3)[CH2:24][OH:25])=[O:28])=[C:30]([F:38])[CH:31]=2)=[CH:4][C:5]([CH:8]2[CH2:9][CH2:10][C:11](=[O:14])[NH:12][CH2:13]2)=[CH:6][N:7]=1