Ethanol → HCID 178418619、化合物

HRID 5981ノート

反応式

HRID 5981 の反応式
[C:1]1([CH:7]2[CH:12]([N:13]3[CH:17]=[CH:16][N:15]=[CH:14]3)[C:11](=O)[C:10]3[CH:19]=[CH:20][CH:21]=[CH:22][C:9]=3[O:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.Cl.[NH2:24][OH:25].[CH2:26]([OH:28])[CH3:27]>N1C=CC=CC=1>[CH2:26]([O:28][C:7](=[O:8])[CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][O:25]/[N:24]=[C:11]1\[CH:12]([N:13]2[CH:17]=[CH:16][N:15]=[CH:14]2)[CH:7]([C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)[O:8][C:9]2[CH:22]=[CH:21][CH:20]=[CH:19][C:10]\1=2)[CH3:27]

参加物

5

反応物 3

HCID 702EthanolHCID 443297Hydroxyamine hydrochlorideHCID 13135472(+-)-2-phenyl-3-(1H-imidazol-1-yl)-2,3-dihydro-4H-benzopyran-4-one

生成物 1

HCID 178418619HCID 178418619、化合物

試薬・触媒・溶媒 1

HCID 1049Pyridine溶媒

実験手順

As an example the intermediate oxime used as starting material can be prepared as follows: (+-)-2-phenyl-3-(1H-imidazol-1-yl)-2,3-dihydro-4H-benzopyran-4-one[J. Het. Chem. 21,311,(1984)], (4 g.; 0.014 moles), is dissolved in pyridine, and hydroxylamine hydrochloride (2.4 g.; 0.034 moles) dissolved in ethanol (20 ml), is added at room temperature to the solution.

後処理

  1. customcan be prepared
  2. additionis added at room temperature to the solution

出典と根拠

ORDレコード
ord-ec948c710b104c45b379cfa5db96a444
出典データセット
uspto-grants-1993_09
特許番号
US05246956

反応ノート

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