1,2-Dimethylimidazole → HCID 86617157、化合物

HRID 606556

反応式

HRID 606556 の反応式
[Cl:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17].[CH3:18][N:19]1[CH:23]=[CH:22][N:21]=[C:20]1[CH3:24]>CC#N>[Cl-:1].[CH3:18][N+:19]1[CH:23]=[CH:22][N:21]([CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17])[C:20]=1[CH3:24]

参加物

4

反応物 2

HCID 156171,2-DimethylimidazoleHCID 209931-Chlorohexadecane

生成物 1

HCID 86617157HCID 86617157、化合物収率 62%

試薬・触媒・溶媒 1

HCID 6342Acetonitrile溶媒

反応条件

温度
80 °C

実験手順

To a 2 L three-necked round bottom flask equipped with overhead mechanical stirrer were added 1-chlorohexadecane (260 g, 1.00 moles), 1,2 dimethylimidazole (91.0 g, 0.95 moles), and CH3CN (500 mL) and the two-phase reaction mixture was vigorously stirred in an oil bath at 80° C. After 72 h, the reaction mixture was cooled to room temperature and the product was crystallized overnight. The crystallized solid was filtered, thoroughly washed with cold CH3CN, and vacuum dried at 70° C. for 3 days to give 1,2-dimethyl-3-hexadecylimidazolium chloride as a slightly off-white solid, 220 g, 62% yield.

後処理

  1. customTo a 2 L three-necked round bottom flask equipped with overhead mechanical stirrer
  2. customthe two-phase reaction mixture
  3. temperaturethe reaction mixture was cooled to room temperature
  4. customthe product was crystallized overnight
  5. filtrationThe crystallized solid was filtered
  6. washthoroughly washed with cold CH3CN, and vacuum
  7. customdried at 70° C. for 3 days

出典と根拠

ORDレコード
ord-a24e5dd4147d4b6e9c248ec7e7069ac6
出典データセット
uspto-grants-2011_03
特許番号
US07915332B2

関連ノート

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