3-Nitrobenzanilide → 3-Aminobenzanilide

HRID 610075

反応式

HRID 610075 の反応式
[N+:1]([C:4]1[CH:5]=[C:6]([CH:16]=[CH:17][CH:18]=1)[C:7]([NH:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)=[O:8])([O-])=O>[Pd].C(O)C>[NH2:1][C:4]1[CH:5]=[C:6]([CH:16]=[CH:17][CH:18]=1)[C:7]([NH:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)=[O:8]

参加物

4

反応物 1

HCID 3477553-Nitrobenzanilide

生成物 1

HCID 843473-Aminobenzanilide収率 90.8%

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 702Ethanol溶媒

実験手順

10% Palladium on carbon (2.0 g) was added to a solution of 3-nitro-N-phenyl-benzamide (20 g, 83 mmol) in ethanol (225 mL) and the mixture was hydrogenated at 45 psi for 2 hours. The mixture was filtered through diatomaceous earth and concentrated to give a colorless solid (mp 118-120° C., 16 g, 90%).

後処理

  1. filtrationThe mixture was filtered through diatomaceous earth
  2. concentrationconcentrated

出典と根拠

ORDレコード
ord-0de9ee7ba0624e6f89c88e7033107b63
出典データセット
uspto-grants-1999_12
特許番号
US05998463

関連ノート

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