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Creatine → Creatine

HRID 613450
ノート
印刷プレビュー

反応式

HRID 613450 の反応式
[C:1]([OH:6])(=[O:5])[C:2](C)=O.C([O-])(=O)C(C)=O.[Mg+2].C([O-])(=O)C(C)=O.C([O-])(=O)C(C)=O.[K+].C([O-])(=O)C(C)=O.[Ca+2].C([O-])(=O)C(C)=O.C([O-])(=O)C(C)=O.[Na+].[Na].C([O-])(=O)C(C)=O.C(NCC(O)=O)(=O)C(C)=O.C([CH:69]([N:73]([C:75](=[NH:77])[NH2:76])C)C(O)=O)(=O)C(C)=O.O=C(C[N:82]([C:84](=[NH:86])[NH2:85])C)O>O.C(O)(=O)C>[O:5]=[C:1]([CH2:2][N:73]([C:75](=[NH:76])[NH2:77])[CH3:69])[OH:6].[O:5]=[C:1]([CH2:2][NH:85][C:84](=[NH:82])[NH2:86])[OH:6]
参加物実験手順出典と根拠反応ノート

参加物

14

反応物 10

HCID 586Creatine4 回HCID 1060Pyruvic Acid3 回HCID 107735Pyruvate3 回HCID 5360545Sodium2 回HCID 6451625PyruvoylglycineHCID 9859191Calcium pyruvateHCID 10219827Magnesium pyruvate
HCID 23662274
Sodium pyruvate
HCID 23678876Propanoic acid, 2-oxo-, potassium salt (1:1)
HCID 131721533Pyruvyl-creatine

生成物 2

HCID 586CreatineHCID 178513022HCID 178513022、化合物

試薬・触媒・溶媒 2

HCID 176Acetic Acid溶媒HCID 962Water溶媒2 回

実験手順

Pyruvic acid is a colorless liquid with an odor resembling that of acetic acid and has a melting point of 13° C. Pyruvic acid is an intermediate in the breakdown of sugars to alcohol by yeast. The mineral salts of pyruvic acid, such as magnesium pyruvate, potassium pyruvate or calcium pyruvate or mixtures thereof are useful in the present invention. Sodium pyruvate is not especially preferred as it is known that sodium is associated with various negative medical conditions such as high blood pressure, water retention and heart disease. Further, certain athletes, such as bodybuilders, desire to present a defined visual image of their body which shows muscle definition and thus, the water retention properties of the sodium salt are not beneficial. Pyruvate precursors in the form of pyruvamides or pyruvyl-amino acids are also useful in the present invention. Pyruvyl-glycine is representative of the useful pyruvyl-amino acids. Another form of pyruvate precursor is pyruvyl-creatine, wherein pyruvate is bonded to creatine either covalently or ionically. Creatine or methylguanidineacetic acid has the chemical formula: ##STR2## and is present in the muscle tissue of vertebrates. It plays an important part in the cycle of chemical changes involving muscular contraction. Normally, creatine is the form in which creatine is excreted. Creatine is formed in the body by the methylation (by methionine) of glycocyamine.

出典と根拠

ORDレコード
ord-3c45540003774589824d60aeb4717e18
出典データセット
uspto-grants-1999_12
DOI
10.6084/m9.figshare.5104873.v1
特許番号
US06008252

反応ノート

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