Butylamine → Hexadecanamide, N-butyl-

HRID 614305ノート

反応式

HRID 614305 の反応式
[C:1](Cl)(=[O:17])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16].[CH2:19]([NH2:23])[CH2:20][CH2:21][CH3:22]>C(OCC)C>[CH2:19]([NH:23][C:1](=[O:17])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16])[CH2:20][CH2:21][CH3:22]

参加物

4

反応物 2

HCID 8007ButylamineHCID 8206Palmitoyl chloride

生成物 1

HCID 9972764Hexadecanamide, N-butyl-

試薬・触媒・溶媒 1

HCID 3283Diethyl Ether溶媒2 回

実験手順

An amount of 137.4 g of palmitoyl chloride in 100 ml of ethyl ether was added, under stirring at room temperature, to 80.5 g of n-butylamine in 700 ml of ethyl ether. Stirring was continued under gentle reflux for one hour. The precipitate was filtered off and thoroughly washed with water. The reaction product was recrystallized from ethanol giving 148.4 g of the title compound, melting point 74°-76° C.

後処理

  1. temperatureunder gentle reflux for one hour
  2. filtrationThe precipitate was filtered off
  3. washthoroughly washed with water
  4. customThe reaction product was recrystallized from ethanol giving 148.4 g of the title compound, melting point 74°-76° C.

出典と根拠

ORDレコード
ord-414bb387c4ef4a389502d402939b919f
出典データセット
uspto-grants-1979_03
特許番号
US04144320

反応ノート

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