Nitric Acid → 3-Bromo-2-nitro-1-benzofuran

HRID 614358

反応式

HRID 614358 の反応式
[Br:1][C:2]1[C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[O:4][CH:3]=1.[N+:11]([O-])([OH:13])=[O:12].N([O-])=O.[Na+]>CO>[Br:1][C:2]1[C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[O:4][C:3]=1[N+:11]([O-:13])=[O:12]

参加物

5

反応物 3

HCID 944Nitric Acid2 回HCID 6405893-Bromo-1-benzofuranHCID 23668193Sodium Nitrite

生成物 1

HCID 135098423-Bromo-2-nitro-1-benzofuran

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

A 5.0 g. sample of powdered 3-bromobenzofuran on a glass dish is placed next to a container of nitric acid. Sodium nitrite is added periodically to the nitric acid, and the entire experiment is covered with a bell jar. After about 15 minutes the powder becomes an oil. After 12 hours the product is dissolved in hot methanol and slowly crystallized by cooling. Recrystallization from methanol provides yellow crystals of 3-bromo-2-nitrobenzofuran, m.p. 130°-132° C. (lit. 132° C.).

後処理

  1. customslowly crystallized
  2. temperatureby cooling
  3. customRecrystallization from methanol

出典と根拠

ORDレコード
ord-e8b879d8638c47dbba8295506a30c2d9
出典データセット
uspto-grants-1979_03
特許番号
US04144347

関連ノート

読み込み中…